The Promise of Neuromodulation
The promise of neuromodulation is aggressively being pursued as the future of OAB treatment.
The mechanism of neuromodulation
Neuromodulation is a common therapy used to treat medical conditions by altering aberrant nerve behavior. Electrical impulses can be delivered to augment nerve conduction, thereby positively influencing nerve communication and end-organ sensation and function. Cardiac pacemakers and pain-control devices are the best-known examples. Nerves innervate most tissue in the body, so aggressive research is underway to afford patients with opportunities to use neuromodulation to treat everything from mood disorders, seizures, and headaches to inflammatory conditions, diabetes and hypertension.
Advantages of neuromodulation
Neuromodulation therapy is delivered to specific nerve targets, thereby avoiding systemic side effects. This advantage often translates to fewer contraindications. Neuromodulation treatment may be titrated to optimize benefit while avoiding sequelae related to excessive dosing. Medications and neurotoxin-based therapies generally are delivered in standard dosing and may not afford this opportunity. Patients often learn to self-adjust their regimens. Research on implanted sacral neuromodulation approaches suggests that the micturition control centers in the brain can be favorably influenced by neuromodulation of peripheral nerves.
Vaginal approach neuromodulation delivery may be the elegant solution
- Restoring proper nerve function
Neuromodulation is a common therapy used to treat medical conditions by altering aberrant nerve behavior. Electrical impulses can be delivered to augment nerve conduction, thereby positively influencing nerve communication and end-organ sensation and function. Cardiac pacemakers and pain-control devices are the best-known examples. Nerves innervate most tissue in the body, so aggressive research is underway to afford patients with opportunities to use neuromodulation to treat everything from mood disorders, seizures, and headaches to inflammatory conditions, diabetes and hypertension.
Advantages of neuromodulation
- Targeted therapy means less systemic side-effects
- Dose control and flexibility of use
- May positively influence bladder control nerves in distant parts of the nervous system
Neuromodulation therapy is delivered to specific nerve targets, thereby avoiding systemic side effects. This advantage often translates to fewer contraindications. Neuromodulation treatment may be titrated to optimize benefit while avoiding sequelae related to excessive dosing. Medications and neurotoxin-based therapies generally are delivered in standard dosing and may not afford this opportunity. Patients often learn to self-adjust their regimens. Research on implanted sacral neuromodulation approaches suggests that the micturition control centers in the brain can be favorably influenced by neuromodulation of peripheral nerves.
Vaginal approach neuromodulation delivery may be the elegant solution
- Continuous and targeted treatment without surgery or an implant
- Ease-of-use may make all the difference in treatment compliance